Re: Neural injury after use of vasopressin and adrenaline during porcine cardiopulmonary resuscitation

Abstract

Dear Editor, Halvorsen and colleagues (1) investigated cerebral and cardiac tissue injury subsequent to use of vasopressin and adrenaline in combination compared with vasopressin alone during cardiopulmonary resuscitation (CPR). They concluded that combined use of vasopressin and adrenaline caused greater signs of cerebral and cardiac injury than use of vasopressin alone during experimental CPR. However, given that epinephrine was administered after 12 min of untreated ventricular fibrillation (VF), these results are not surprising.