Comment on: ‘Mean platelet volume could be a promising biomarker to monitor dietary compliance in celiac disease’

Abstract

I have read the article published by Purnak et al. with great interest (1). They examined the mean platelet volume (MPV), an indicator of platelet reactivity, in patients with celiac disease. They showed that MPV values in patients with celiac disease were significantly higher than in controls. They concluded that MPV could be a useful clinical marker for monitoring of dietary compliance in celiac disease patients. This is a very interesting study. However, I would like to put forward some minor criticism with regard to some methodological and pathophysiological aspects.