Acute renal failure in severe pancreatitis: A population-based study

  • Hung-Yuan Lin Shih-Hsin University, Department of Information Management, Taiwan, Republic of China
  • Jiun-I Lai National Yang-Ming University School of Medicine, Taiwan, Republic of China; and Department of Medicine, National Yang-Ming University Hospital, Taiwan, Republic of China
  • Yi-Chun Lai National Yang-Ming University School of Medicine, Taiwan, Republic of China; and Department of Medicine, National Yang-Ming University Hospital, Taiwan, Republic of China
  • Po-Chou Lin National Yang-Ming University School of Medicine, Taiwan, Republic of China; and Department of Medicine, National Yang-Ming University Hospital, Taiwan, Republic of China
  • Shih-Chieh Chang National Yang-Ming University School of Medicine, Taiwan, Republic of China; and Department of Medicine, National Yang-Ming University Hospital, Taiwan, Republic of China
  • Gau-Jun Tang National Yang-Ming University School of Medicine, Taiwan, Republic of China; and Department of Medicine, National Yang-Ming University Hospital, Taiwan, Republic of China
Keywords: Acute renal failure, intensive care, severe acute pancreatitis

Abstract

Introduction. Acute pancreatitis (AP) is a common illness with varied mortality and morbidity. Patients with AP complicated with acute renal failure (ARF) have higher mortality than patients with AP alone. Although ARF has been proposed as a leading mortality cause for AP patients admitted to the ICU, few studies have directly analyzed the relationship between AP and ARF.

Methods. We performed a retrospective study using the population-based database from the Taiwan National Health Insurance Research Database (NHIRD). In the period from 1 January 2005 to 31 December 2005, every patient with AP admitted to the ICU was included and assessed for the presence of ARF and mortality risk.

Results. In year 2005, there were a total of 221,101 admissions to the ICU. There were 1,734 patients with AP, of which 261 (15.05%) patients also had a diagnosis of ARF. Compared to sepsis and other critical illness, patients with AP had a higher risk of having a diagnosis of ARF, and patients with both diagnoses had a higher mortality rate in the same ICU hospitalization.

Conclusion. AP is associated with a higher risk of ARF, and, when both conditions exist, a higher risk of mortality is present.

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Published
2011-01-20
How to Cite
Lin H.-Y., Lai J.-I., Lai Y.-C., Lin P.-C., Chang S.-C., & Tang G.-J. (2011). Acute renal failure in severe pancreatitis: A population-based study. Upsala Journal of Medical Sciences, 116(2), 155–159. https://doi.org/10.3109/03009734.2010.547636
Section
Original Articles