A patient with Graves' disease who survived despite developing thyroid storm and lactic acidosis

  • TETSUHIRO YOSHINO Department of Internal Medicine, Nerima General Hospital, Asahigaoka, Nerima-ku, Tokyo, Japan
  • DAISUKE KAWANO Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • TAKEO AZUHATA Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • TSUKASA KUWANA Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • RIKIMARU KOGAWA Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • ATSUSHI SAKURAI Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • KATSUHISA TANJOH Division of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, Oyaguchi Kamimachi, Itabashi-ku, Tokyo, Japan
  • TATSUO YANAGAWA Department of Internal Medicine, Nerima General Hospital, Asahigaoka, Nerima-ku, Tokyo, Japan
Keywords: Graves’ disease, hypoglycemia, lactic acidosis, thyroid storm

Abstract

A 56-year-old woman with Graves' disease presented with the complaints of diarrhea and palpitations. Physical examination and laboratory data revealed hypothermia and signs of mild hyperthyroidism, heart failure, hepatic dysfunction with jaundice, hypoglycemia, and lactic acidosis. The patient was diagnosed as having developed the complication of thyroid storm in the absence of marked elevation of the thyroid hormone levels, because of the potential hepatic and cardiac dysfunctions caused by heavy alcohol drinking. A year later, after successful treatment, the patient remains well without any clinical evidence of heart failure or hepatic dysfunction. Thyroid storm associated with lactic acidosis and hypothermia is a serious condition and has rarely been reported. Prompt treatment is essential even if the serum thyroid hormone levels are not markedly elevated. We present a report about this patient, as her life could eventually be saved.

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Published
2010-08-23
How to Cite
YOSHINO, T., KAWANO, D., AZUHATA, T., KUWANA, T., KOGAWA, R., SAKURAI, A., TANJOH, K., & YANAGAWA, T. (2010). A patient with Graves’ disease who survived despite developing thyroid storm and lactic acidosis. Upsala Journal of Medical Sciences, 115(4), 282–286. https://doi.org/10.3109/03009734.2010.486908
Section
Short Reports