Anaplastic large-cell lymphoma with atypical chromosomal translocation t(2;5) and hypophyseal tumor

LEI  WANG; YIN  TONG; ZHIMEI  CHEN; WEILAI  XU; JIE  JIN

doi:10.3109/03009734.2010.500061

Anaplastic large-cell lymphoma with atypical chromosomal translocation t(2;5) and hypophyseal tumor

LEI WANG Department of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China
YIN TONG Department of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China
ZHIMEI CHEN Institute of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China
WEILAI XU Department of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China
JIE JIN Department of Hematology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, P. R. China

DOI: https://doi.org/10.3109/03009734.2010.500061

Keywords: ALCL, ALK , chromosomal translocation, hypophyseal tumor

Abstract

Anaplastic large T-cell lymphoma (ALCL) is frequently associated with the t(2;5)(p23;q35). Here, we report a case of ALCL with an atypical translocation of t(2;5)(p24;q13) and other complex translocations. This complex abnormal karyotype may result in chemotherapy resistance and a poor outcome. Interestingly, a hypophyseal tumor was detected simultaneously by magnetic resonance imaging in this case. We think it is probable that the tumor in the hypophysis might be associated with the ALCL.

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Published

2010-10-27

How to Cite

WANG L., TONG Y., CHEN Z., XU W., & JIN J. (2010). Anaplastic large-cell lymphoma with atypical chromosomal translocation t(2;5) and hypophyseal tumor. Upsala Journal of Medical Sciences, 115(4), 287–290. https://doi.org/10.3109/03009734.2010.500061

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Issue

Vol. 115 No. 4 (2010): Upsala J Med Sci

Section

Case Reports

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