Factors related to curved femur in elderly Japanese women

  • Hiroyuki Tsuchie Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
  • Naohisa Miyakoshi Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
  • Yuji Kasukawa Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
  • Seietsu Senma Division of Orthopedic Surgery, Nakadori General Hospital, 3-15, Misono-cho, Minami-dori, Akita 010-8577, Japan
  • Yuichiro Narita Division of Orthopedic Surgery, Nakadori General Hospital, 3-15, Misono-cho, Minami-dori, Akita 010-8577, Japan
  • Seiya Miyamoto Division of Orthopedic Surgery, Nakadori General Hospital, 3-15, Misono-cho, Minami-dori, Akita 010-8577, Japan
  • Yuji Hatakeyama Division of Orthopedic Surgery, Nakadori General Hospital, 3-15, Misono-cho, Minami-dori, Akita 010-8577, Japan
  • Kana Sasaki Division of Orthopedic Surgery, Nakadori General Hospital, 3-15, Misono-cho, Minami-dori, Akita 010-8577, Japan
  • Yoichi Shimada Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
Keywords: 25-Hydroxyvitamin D, atypical femoral fracture, curved femur, osteomalacia, women

Abstract

Background: Multiple factors are involved in the development of atypical femoral fractures, and excessive curvature of the femur is thought to be one of them. However, the pathogenesis of femoral curvature is unknown. We evaluated the influence of factors related to bone metabolism and posture on the development of femoral curvature.

Methods: A total of 139 women participated in the present study. Curvatures were measured using antero-posterior and lateral radiography of the femur. We evaluated some bone and vitamin D metabolism markers in serum, the bone mineral density (BMD), lumbar spine alignment, and pelvic tilt.

Results: We divided the women into two groups, curved and non-curved groups, based on the average plus standard deviation as the cut-off between the groups. When univariate logistic regression analysis was performed to detect factors affecting femoral curvature, the following were identified as indices significantly affecting the curvature: age of the patients, serum concentrations of calcium, intact parathyroid hormone, pentosidine, homocysteine and 25-hydroxyvitamin D (25(OH)D), and BMD of the proximal femur (P < 0.05) both in the lateral and anterior curvatures. When we used multivariate analyses to assess these factors, only 25(OH)D and age (lateral and anterior standardized odds ratio: 0.776 and 0.385, and 2.312 and 4.472, respectively) affected the femoral curvature (P < 0.05).

Conclusion: Femoral curvature is strongly influenced by age and serum vitamin D.

Downloads

Download data is not yet available.
Published
2016-05-26
How to Cite
Tsuchie, H., Miyakoshi, N., Kasukawa, Y., Senma, S., Narita, Y., Miyamoto, S., Hatakeyama, Y., Sasaki, K., & Shimada, Y. (2016). Factors related to curved femur in elderly Japanese women. Upsala Journal of Medical Sciences, 121(3), 170–173. https://doi.org/10.1080/03009734.2016.1185200
Section
Original Articles

Most read articles by the same author(s)