Osteosarcoma of the Proximal Fibula. An analysis of 13 cases in the northern Japan

  • Shu Takahashi
  • Akira Ogose
  • Takahiro Tajino
  • Toshihisa Osanai
  • Kyoji Okada


Osteosarcoma is the most common form of malignant bone tumor that occurs during childhood and adolescence. The proximal fibula is a relatively rare site for osteosarcoma. We reviewed 305 cases of osteosarcoma registered at the Tohoku Musculoskeletal Tumor Society (TMTS) between 1975 and 1999. Thirteen patients (4.3%) had their osteosarcomas localized in the proximal fibula. Conventional fibroblastic osteosarcoma accounted for 46% of the cases in this series. Limb-sparing surgery was performed in all 13 patients during initial surgery, and the peroneal nerve was preserved in 4 cases. These 4 cases developed local recurrences, but additional wide excision or radiation had a beneficial effect on the recurrences. In our series, the patients showed a 5-year survival rate 76 per cent. The postoperative function of the knee remained good despite various reattachment procedures of lateral co-lateral ligament. As well as resection of the proximal fibula, our results indicate that osteosarcoma of the proximal fibula has a good prognosis for cases who undergo adequate initial surgery.


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How to Cite
Takahashi S., Ogose A., Tajino T., Osanai T., & Okada K. (2009). Osteosarcoma of the Proximal Fibula. An analysis of 13 cases in the northern Japan. Upsala Journal of Medical Sciences, 112(3), 366–372. https://doi.org/10.3109/2000-1967-209
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