Inhibition of Carbonic Anhydrase in the Lens does not Induce Myopia in Cynomolgus Monkeys

Per J.  Wistrand

doi:10.3109/2000-1967-164

Inhibition of Carbonic Anhydrase in the Lens does not Induce Myopia in Cynomolgus Monkeys

Per J. Wistrand Department of Ophthalmology, Akademiska Sjukhuset, University of Uppsala, Uppsala, Sweden

DOI: https://doi.org/10.3109/2000-1967-164

Abstract

Refraction was measured in eyes of cynomolgus (Macaca irus) monkeys, before and during continuous intravenous infusion of large doses of the carbonic anhydrase (CA) inhibitors acetazolamide and ethoxzolamide. No changes of refraction were seen. Therefore, inhibition of CA in lens, cornea and retina does not appear to be the cause of the transient myopia and associated symptoms, occasionally observed in patients treated with CA inhibitors.

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Published

2009-07-12

How to Cite

Wistrand P. J. (2009). Inhibition of Carbonic Anhydrase in the Lens does not Induce Myopia in Cynomolgus Monkeys. Upsala Journal of Medical Sciences, 106(2), 117–121. https://doi.org/10.3109/2000-1967-164

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Issue

Vol. 106 No. 2 (2001): Upsala J Med Sci

Section

Original Articles

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