HLA-A, B, C and DR in Hepatitis B Virus (HBV)-Related Liver Cirrhosis: A Study of 851 Elderly Subjects

  • G. Ricci
  • B. Ghiazza
  • G. Bombelli
  • E. Russo
  • T. Illeni

Abstract

The possible correlation between HLA system and liver cirrhosis secondary to HBV infection has been studied in 102 hospitalized elderly patients affected by liver cirrhosis (histologically proven) and 749 elderly health controls. Increased frequencies of HLA-A2, Cw4, Cw5, DR4, DR5 and DR7 have been observed in patients with liver cirrhosis and previous HBV infection, while a lower frequency of HLA-A2 and higher frequencies of HLA-A3, B35, Cw4, DR3 have been observed in patients without previous HBV infection when compared with controls.

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Published
2010-01-18
How to Cite
Ricci G., Ghiazza B., Bombelli G., Russo E., & Illeni T. (2010). HLA-A, B, C and DR in Hepatitis B Virus (HBV)-Related Liver Cirrhosis: A Study of 851 Elderly Subjects. Upsala Journal of Medical Sciences, 98(2). https://doi.org/10.3109/03009739309179311
Section
Original Articles