The Relationship between the Pharmacokinetics and Pharmacodynamics of Spinal Opioids:

Staffan  Sjöström

doi:10.3109/03009738809178530

The Relationship between the Pharmacokinetics and Pharmacodynamics of Spinal Opioids

Minireview based on a doctoral thesis

Staffan Sjöström Department of Anesthesiology and Intensive Care, University Hospital, Uppsala, Sweden

DOI: https://doi.org/10.3109/03009738809178530

Abstract

Spinal opioids have been used clinically since the late seventies to treat acute, traumatic, obstetric and chronic pain. In this article the influence of the pharmacokinetics on the dynamics of intrathecal and epidural opioid administration are discussed with reference to current knowledge.

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Published

1988-09-01

How to Cite

Sjöström S. (1988). The Relationship between the Pharmacokinetics and Pharmacodynamics of Spinal Opioids: Minireview based on a doctoral thesis. Upsala Journal of Medical Sciences, 93(2), 101-120. https://doi.org/10.3109/03009738809178530

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Issue

Vol. 93 No. 2 (1988): Upsala J Med Sci

Section

Mini Review

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