Effect of Nicotinic Acid on the Posttraumatic Increase in Free Fatty Acids and Fibrinolysis Inhibition Activity in the Rat

  • Thomas Wegener Institute of Forensic Medicine, University of Uppsala, Uppsala, Sweden
  • Lars Bagge Institute of Forensic Medicine, University of Uppsala, Uppsala, Sweden
  • Tom Saldeen Institute of Forensic Medicine, University of Uppsala, Uppsala, Sweden

Abstract

Nicotinic acid effectively inhibited the posttraumatic increase in both free fatty acids (FFA) and fibrinolysis inhibition activity (FIA) in the blood in rats, indicating that FFA might be involved in the posttraumatic increase of FIA. The FIA in the liver was greater than that in other organs studied and was increased in the posttraumatic phase. The possible role of the liver in the posttraumatic increase of FIA is discussed.

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Published
1979-09-01
How to Cite
Wegener T., Bagge L., & Saldeen T. (1979). Effect of Nicotinic Acid on the Posttraumatic Increase in Free Fatty Acids and Fibrinolysis Inhibition Activity in the Rat. Upsala Journal of Medical Sciences, 84(3), 195-201. https://doi.org/10.3109/03009737909179156
Section
Original Articles