Hepatic Triglyceride and Lipoprotein Lipase Activities of Post-heparin Plasma in Normals and Hypertriglyceridemics

Abstract

Post-heparin plasma hepatic triglyceride lipase (H-TGL) and lipoprotein lipase (LPL) activities were 8–34 and 3.5–21 (range) μmol/ml/hr respectively in males with normal serum lipid concentrations. In females the corresponding values were 4–25 and 4–16 μmol/ml/hr. No significant differences were observed between ages or between the two sexes.

Male patients with hypertriglyceridaemia had similar activities of H-TGL but significantly lower values for LPL activities than the control males.

Significant linear correlations were found between serum triglyceride concentrations and LPL activities both for males (coefficient of correlation = r = −0.64) and for females (r = −0.62).