Gastric Secretion in Hyperparathyroid Subjects before and after Parathyroid Surgery

Abstract

In 61 patients with verified hyperparathyreoidism (HPT) the influence of parathyroidectomy on gastric acid and mucus secretion (sialic acid) as well as on serum gastrin concentration was studied. Patients with both normocalcemic (N-HPT) and hypercakemic HPT (H-HPT) have been investigated. The pre-operative serum gastrin level was essentially similar in patients with N-HPT and H-HPT. The serum gastrin level was not influenced by the parathyroidectomy. The gastric acid secretion and the content of sialic acid in the gastric juice were unaffected by parathyroidectomy. Achylia or hypochylia after two different doses of submaximal histamine stimulation were found in 13 patients.