An in-vitro Method of Investigating the Rates of Transcapillary Exchange and Net Filtration by Single-injection Technique
Abstract
A method of preparing a cat's hind leg that is suitable for studying the rates of transcapillary solute and solvent movements is described. The preparation may be perfused at any desired venous pressure. A bolus may be injected into the capillary network without altering either the perfusion pressure or the flow rate (while continuously recording the weight of the isolated leg). A new method of calculating extractions is introduced. This method uses the estimate of the correlation between the relative concentrations of reference and test substances in the venous outflow.
Downloads
Authors retain copyright of their work, with first publication rights granted to Upsala Medical Society. Read the full Copyright- and Licensing Statement.