@article{Tholander_Koliadi_Botling_Dahlstrand_Von Heideman_Ahlström_Öberg_Ullenhag_2020, title={Complete response with combined BRAF and MEK inhibition in BRAF mutated advanced low-grade serous ovarian carcinoma}, volume={125}, url={https://ujms.net/index.php/ujms/article/view/5716}, DOI={10.1080/03009734.2020.1826612}, abstractNote={<p>More effective treatments are needed for low-grade serous ovarian carcinoma (LGSOC). Our patient, who suffers from metastatic LGSOC, had received all established treatments. Sequencing analysis revealed an activating BRAF mutation. Therefore, combined treatment with BRAF and MEK inhibitors, which is the gold standard in malignant melanoma, was initiated. After eight months of therapy, the response was assessed as complete and the treatment is still, 3.5 years after initiation, of benefit. To our knowledge, no complete response on combined BRAF and MEK inhibitor treatment of low-grade serous ovarian cancer has previously been reported.</p&gt;}, number={4}, journal={Upsala Journal of Medical Sciences}, author={Tholander Bengt and Koliadi Anthoula and Botling Johan and Dahlstrand Hanna and Von Heideman Anne and Ahlström Håkan and Öberg Kjell and Ullenhag Gustav J.}, year={2020}, month={Oct.}, pages={325–329} }