@article{Berne_Andersson_1981, title={Lipid Metabolism of Isolated Mouse Pancreatic Islets Maintained in Culture at Different Glucose Concentrations}, volume={86}, url={https://ujms.net/index.php/ujms/article/view/7153}, DOI={10.3109/03009738109179210}, abstractNote={<p>The lipid metabolism of isolated mouse pancreatic islets, which had been cultured for one week at 3.3 or 16.7 mM glucose, was examined in short-term experiments performed at the end of the culture period. It was found that: a) highglucose cultured islets oxidized palmitate at a higher rate: and b) both groups of cultured islets increased the rate of incorporation of (U-<sup>14</sup>C)-glucose into triacylglycerols and phospholipids in response to an acute glucose challenge. This latter effect was, however, more pronounced after culture at a high glucose concentration. The present data suggest that long-term exposure to high concentrations of glucose leads to a general increase of islet oxidative metabolism. Moreover, high glucose culture seems to induce an increased conversion of carbohydrates into triacylglycerols and membrane phospholipids.</p&gt;}, number={1}, journal={Upsala Journal of Medical Sciences}, author={Berne Christian and Andersson Arne}, year={1981}, month={Mar.}, pages={55-61} }