@article{Söderström_Forslund_Johansson_Ottenblad_Rosenblad_2022, title={Associations between dietary advice on modified fibre and lactose intakes and nutrient intakes in men with prostate cancer undergoing radiotherapy}, volume={127}, url={https://ujms.net/index.php/ujms/article/view/8261}, DOI={10.48101/ujms.v127.8261}, abstractNote={<p><strong>Objectives</strong>: A variety of non-evidence-based dietary advice on modified fibre and lactose intakes are provided to patients undergoing pelvic radiotherapy to counteract treatment-related bowel symptoms. More knowledge on the nutritional consequences of such advice is needed. This study aimed to explore how advice on modified fibre and lactose intakes during pelvic radiotherapy was associated with nutrient intakes amongst patients with prostate cancer.</p> <p><strong>Methods</strong>: A total of 77 Swedish men who underwent radiotherapy (50/2 Gy + boost 20–30 Gy) in 2009–2014 due to prostate cancer were given dietary advice at radiotherapy onset (baseline) and at 4 and 8 weeks after radiotherapy onset, to modify their fibre and lactose intakes. At baseline, the participants completed a food frequency questionnaire (FFQ) and a 24-h dietary recall. At 4 and 8 weeks, the participants completed the FFQ and a 4-day estimated food record.</p> <p>Fibre and lactose intakes were measured by intake scores calculated from the FFQs. Multiple linear regression models were used to analyse associations between intake scores and fibre- and lactose-related nutrients.</p> <p><strong>Results</strong>: In adjusted analyses, there were few significant associations between dietary advice on modified fibre and lactose intakes and observed intakes of fibre- and lactose-related nutrients. A more modified lactose intake was thus associated with a lower intake of calcium (<em>P</em>&nbsp;= 0.041), whilst a more modified fibre intake was associated with a higher value for the change in intake of vitamin C (<em>P</em>&nbsp;= 0.016).</p> <p><strong>Conclusions</strong>: Dietary advice on modified fibre and lactose intake was in most cases not significantly associated with altered nutrient intakes, rather the energy and nutrient intakes were mostly stable during the pelvic radiotherapy. More research is needed on the nutritional consequences of dietary advice on modified fibre and lactose intakes to reach consensus on if they should continue to be provided in the clinic.</p&gt;}, number={1}, journal={Upsala Journal of Medical Sciences}, author={Söderström Lisa and Forslund Marina and Johansson Birgitta and Ottenblad Anna and Rosenblad Andreas}, year={2022}, month={Jun.} }