The Influence of Hypercalcemia on Gastric Secretion and Serum Gastrin Concentration in Intact and Thyro-parathyroidectomized Rats

Abstract

Gastric acidity and serum gastrin concentration were measured in thyro-parathyroidectomized and sham-operated rats after calcium infusion. A moderate hydrogen ion decrease, and unchanged chloride ion concentration and plasma gastrin level were demonstrated in both experimental groups, indicating a different calcium-gastrin mechanism from that in man.