Ultrastructure of Rat Pancreatic Islets in Long Term Tissue Culture

  • GÖSTA HULTQUIST
  • JAN PONTEN

Abstract

Islets of Langerhans in atrophic pancreas of duct-ligated rats have been explanted in organ culture and 47 explants have been studied by electron microscopy. The ultrastructure was essentially preserved for at least 4 weeks of cultivation leaving aside rapidly vanishing degenerative alterations during the first few days in vitro. Two different concentrations of glucose were used (0.1 and 0.4 g/100). At both levels, β cell granules showed increased variability in shape, size and electron density. Even at the higher glucose concentration the number of granules was about the same as at the lower one.

Downloads

Download data is not yet available.
Published
1974-03-01
How to Cite
HULTQUIST G., & PONTEN J. (1974). Ultrastructure of Rat Pancreatic Islets in Long Term Tissue Culture. Upsala Journal of Medical Sciences, 79(1), 21-27. https://doi.org/10.3109/03009737409178386
Section
Original Articles

Most read articles by the same author(s)